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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2104565Generated: October 30, 2026

4-(4'-Formyl-3'-methoxyphenoxy)butyric acid → 4-{4-[({3-[3-Benzoyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenyl}Amino)Methyl]-3-Methoxyphenoxy}Butanoic Acid

https://huagongshe.com/reaction/2104565

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(4'-Formyl-3'-methoxyphenoxy)butyric acidHCID 2759226—
Reactant[4-(3-Aminophenyl)-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)MethanoneHCID 11326798—
Product4-{4-[({3-[3-Benzoyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenyl}Amino)Methyl]-3-Methoxyphenoxy}Butanoic AcidHCID 66913564—

Reaction Steps

The title compound was prepared from [4-(3-amino-phenyl)-8-trifluoromethyl-quinolin-3-yl]-phenyl-methanone and 4-(4-formyl-3-methoxy-phenoxy)-butyric acid according to the procedure of Example 66. MS (ESI) m/z 613.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576215B2
Source datasetuspto-grants-2009_08
ORD IDord-8908e746b2db4ebbbd8caec6c50eeb5c
Source noteuspto-grants-2009_08