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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2104585Generated: October 30, 2026

4-(3-Allyl-4-oxo-2-thioxo-thiazolidin-5-ylidenemethyl)-benzaldehyde → 3-Allyl-5-{4-[({3-[3-Benzoyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenyl}Amino)Methyl]Benzylidene}-2-THIOXO-1,3-Thiazolidin-4-One

https://huagongshe.com/reaction/2104585

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(3-Allyl-4-oxo-2-thioxo-thiazolidin-5-ylidenemethyl)-benzaldehydeHCID 349350—
Reactant[4-(3-Aminophenyl)-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)MethanoneHCID 11326798—
Product3-Allyl-5-{4-[({3-[3-Benzoyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenyl}Amino)Methyl]Benzylidene}-2-THIOXO-1,3-Thiazolidin-4-OneHCID 72827683—

Reaction Steps

The title compound was prepared from [4-(3-amino-phenyl)-8-trifluoromethyl-quinolin-3-yl]-phenyl-methanone and 4-(3-allyl-4-oxo-2-thioxo-thiazolidin-5-ylidenemethyl)-benzaldehyde according to the procedure of Example 66. MS (ES) m/z 663.8.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576215B2
Source datasetuspto-grants-2009_08
ORD IDord-92cc063dd96c444ea99dcc95c4f90eb9
Source noteuspto-grants-2009_08