HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzeneacetaldehyde, 3-methyl- → 3-[3-(3-Methylphenyl)-8-(trifluoromethyl)quinolin-4-yl]phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzeneacetaldehyde, 3-methyl- | HCID 175272 | — |
| Reactant | [2-Amino-3-(trifluoromethyl)phenyl](3-hydroxyphenyl)methanone | HCID 66586253 | — |
| Product | 3-[3-(3-Methylphenyl)-8-(trifluoromethyl)quinolin-4-yl]phenol | HCID 66914158 | — |
Reaction Steps
The title compound was prepared from [2-amino-3-(trifluoromethyl)phenyl]-(3-hydroxy-phenyl)methanone and m-Tolyl-acetaldehyde following the procedure of Example 457: MS (ES) m/z 378.0; HRMS: calcd for C23H16F3NO+H+, 380.12567; found (ESI, [M+H]+), 380.1263.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07576215B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-18a7aa0c7d7f440eafc450720771fc46 |
| Source note | uspto-grants-2009_08 |