HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2,4,6-Trimethylphenyl)acetaldehyde → 3-[3-Mesityl-8-(Trifluoromethyl)Quinolin-4-yl]Phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2,4,6-Trimethylphenyl)acetaldehyde | HCID 300382 | — |
| Reactant | [2-Amino-3-(trifluoromethyl)phenyl](3-hydroxyphenyl)methanone | HCID 66586253 | — |
| Product | 3-[3-Mesityl-8-(Trifluoromethyl)Quinolin-4-yl]Phenol | HCID 66914482 | — |
Reaction Steps
The title compound was prepared from [2-amino-3-(trifluoromethyl)phenyl]-(3-hydroxy-phenyl)methanone and (2,4,6-Trimethyl-phenyl)-acetaldehyde following the procedure of Example 457: MS (ES) m/z 405.9; HRMS: calcd for C25H20F3NO+H+, 408.15697; found (ESI, [M+H]+), 408.1573.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07576215B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-5df03219e1d047838923be5715e5b9fc |
| Source note | uspto-grants-2009_08 |