HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(3-(Trifluoromethyl)phenyl)acetaldehyde → 3-{8-(Trifluoromethyl)-3-[3-(Trifluoromethyl)Phenyl]Quinolin-4-yl}Phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(3-(Trifluoromethyl)phenyl)acetaldehyde | HCID 21246339 | — |
| Reactant | [2-Amino-3-(trifluoromethyl)phenyl](3-hydroxyphenyl)methanone | HCID 66586253 | — |
| Product | 3-{8-(Trifluoromethyl)-3-[3-(Trifluoromethyl)Phenyl]Quinolin-4-yl}Phenol | HCID 86598757 | — |
Reaction Steps
The title compound was prepared from [2-amino-3-(trifluoromethyl)phenyl]-(3-hydroxy-phenyl)methanone and (3-Trifluoromethyl-phenyl)-acetaldehyde following the procedure of Example 457: HRMS: calcd for C23H13F6NO+H+, 434.09741; found (ESI, [M+H]+), 434.0993.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07576215B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-12fcf43834994e81a94a35afb9d19206 |
| Source note | uspto-grants-2009_08 |