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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2104634Generated: October 30, 2026

2-Fluoro-3-(trifluoromethyl)benzophenone → [2-Methyl-4-Phenyl-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)Methanone

https://huagongshe.com/reaction/2104634

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-3-(trifluoromethyl)benzophenoneHCID 2737552—
ReactantHCID 21555860HCID 21555860—
Product[2-Methyl-4-Phenyl-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)MethanoneHCID 66914452—

Reaction Steps

[2-amino-3-(trifluoromethyl)phenyl](phenyl)methanone: The title compound was prepared from (2-Fluoro-3-trifluoromethyl-phenyl)-phenyl-methanone following the procedure of Example 457, Step 3: MS (ESI) m/z 266; HRMS: calcd for C14H10F3NO+H+, 266.07872; found (ESI, [M+H]+), 266.0771

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576215B2
Source datasetuspto-grants-2009_08
ORD IDord-fb090ee712ef4382a1c34b2794ea356c
Source noteuspto-grants-2009_08