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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2104668Generated: October 26, 2026

4-(Bromomethyl)benzoic acid → 4-({3-[3-Phenyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenoxy}Methyl)Benzoic Acid

https://huagongshe.com/reaction/2104668

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Bromomethyl)benzoic acidHCID 22599—
Reactant3-(3-Phenyl-8-trifluoromethyl-quinolin-4-yl)-phenolHCID 66586292—
Product4-({3-[3-Phenyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenoxy}Methyl)Benzoic AcidHCID 66914172—

Reaction Steps

The title compound was prepared from [3-(3-Phenyl-8-trifluoromethyl-quinolin-4-yl)-phenol and 4-Bromomethyl-benzoic acid following the procedure of Example 1: mp 108-112° C.; MS m/z 500; HRMS: calcd for C30H20F3NO3+H+, 500.14680; found (ESI, [M+H]+), 500.1461.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576215B2
Source datasetuspto-grants-2009_08
ORD IDord-c154594799bb4e8bb91fed83d22089f8
Source noteuspto-grants-2009_08