HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Bromomethyl)-3-fluorobenzoic acid → 4-({3-[3-Benzyl-8-(Trifluoromethyl)Quinolin-4-yl] Phenoxy}Methyl)-3-Fluorobenzoic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Bromomethyl)-3-fluorobenzoic acid | HCID 15129929 | — |
| Reactant | 3-[3-Benzyl-8-(trifluoromethyl)quinolin-4-yl]phenol | HCID 53630755 | — |
| Product | 4-({3-[3-Benzyl-8-(Trifluoromethyl)Quinolin-4-yl] Phenoxy}Methyl)-3-Fluorobenzoic Acid | HCID 66913557 | — |
Reaction Steps
The title compound was prepared from 3-(3-Benzyl-8-trifluoromethyl-quinolin-4-yl)-phenol and 4-Bromomethyl-3-fluoro-benzoic acid following the procedure of Example 478: MS m/z 532; MS m/z 530; HRMS: calcd for C31H21F4NO3+H+, 532.15303; found (ESI, [M+H]+), 532.153;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07576215B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-ef069c005d174e28bd79087ec40cfbd0 |
| Source note | uspto-grants-2009_08 |