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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2104678Generated: November 1, 2026

Methyl 4-(bromomethyl)benzoate → Methyl-4-[(4-{3-[3-Benzyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenoxy}Phenoxy) Methyl]Benzoate

https://huagongshe.com/reaction/2104678

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-(bromomethyl)benzoateHCID 256687—
ReactantHCID 16718799HCID 16718799—
ProductMethyl-4-[(4-{3-[3-Benzyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenoxy}Phenoxy) Methyl]BenzoateHCID 66914534—

Reaction Steps

The title compound was prepared from 4-{3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]-phen-oxy}phenol (0.1 g, 0.0002 mole) and 4-Bromomethyl-benzoic acid methyl ester (0.057 g, 0.00024 mole) following the procedure of Example 478: MS (ESI) [M+H]+), 620.0.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576215B2
Source datasetuspto-grants-2009_08
ORD IDord-e843122475824e3fbc8513f1650118c7
Source noteuspto-grants-2009_08