HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-(bromomethyl)benzoate → 4-[(4-{3-[3-Benzyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenoxy}Phenoxy)Methyl]Benzoic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-(bromomethyl)benzoate | HCID 256687 | — |
| Reactant | HCID 16718799 | HCID 16718799 | — |
| Product | 4-[(4-{3-[3-Benzyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenoxy}Phenoxy)Methyl]Benzoic Acid | HCID 66913660 | — |
Reaction Steps
The title compound was prepared from 4-{3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]-phen-oxy}phenol (0.1 g, 0.0002 mole) and 4-Bromomethyl-benzoic acid methyl ester (0.057 g, 0.00024 mole) with subsequent hydrolysis following the procedure of Example 515: MS (ES) m/z 603.9; HRMS: calcd for C37H26F3NO4+H+, 606.18867; found (ESI, [M+H]+), 606.1894.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07576215B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-86b4e21e2e364da4b3683614de439df5 |
| Source note | uspto-grants-2009_08 |