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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2104699Generated: October 27, 2026

1-Methylindole-2-carboxaldehyde → 1H-Indole-2-methanamine, 1-methyl-N-[3-[3-(phenylmethyl)-8-(trifluoromethyl)-4-quinolinyl]phenyl]-

https://huagongshe.com/reaction/2104699

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methylindole-2-carboxaldehydeHCID 267164—
Reactant3-(3-Benzyl-8-trifluoromethyl-quinolin-4-yl)-phenylamineHCID 11234297—
Product1H-Indole-2-methanamine, 1-methyl-N-[3-[3-(phenylmethyl)-8-(trifluoromethyl)-4-quinolinyl]phenyl]-HCID 45272392—

Reaction Steps

The title compound was prepared from {3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amine and 1-methylindole-2-carboxaldehyde according to the procedure of step 1, Example 66. MS (ESI) m/z 522.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576215B2
Source datasetuspto-grants-2009_08
ORD IDord-d3a2db5adaa243c0be607ab9d81ac00a
Source noteuspto-grants-2009_08