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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2104710Generated: October 31, 2026

Methyl 2-(4-(bromomethyl)phenyl)-2-methylpropanoate → 2-[4-({3-[3-Benzyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenoxy}Methyl)Phenyl]-2-Methylpropanoic Acid

https://huagongshe.com/reaction/2104710

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-(4-(bromomethyl)phenyl)-2-methylpropanoateHCID 18423131—
Reactant3-[3-Benzyl-8-(trifluoromethyl)quinolin-4-yl]phenolHCID 53630755—
Product2-[4-({3-[3-Benzyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenoxy}Methyl)Phenyl]-2-Methylpropanoic AcidHCID 16718750—

Reaction Steps

Prepared using the procedure in Example 56 except using 3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenol and 2-(4-Bromomethyl-phenyl)-2-methyl-propionic acid methyl ester as the halide. MS (ESI) m/z 556.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576215B2
Source datasetuspto-grants-2009_08
ORD IDord-ebc0ccc421764deaaa783b2720118751
Source noteuspto-grants-2009_08