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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2104712Generated: October 31, 2026

3-[3-Benzyl-8-(trifluoromethyl)quinolin-4-yl]phenol → 2-({3-[3-Benzyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenoxy}Methyl)Terephthalonitrile

https://huagongshe.com/reaction/2104712

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-[3-Benzyl-8-(trifluoromethyl)quinolin-4-yl]phenolHCID 53630755—
Reactant2,5 DicyanobenzylbromideHCID 86598765—
Product2-({3-[3-Benzyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenoxy}Methyl)TerephthalonitrileHCID 66913701—

Reaction Steps

The title compound was prepared from 3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenol and 2,5 dicyanobenzylbromide as in the procedure of Example 43. MS (ESI) m/z 520.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576215B2
Source datasetuspto-grants-2009_08
ORD IDord-c6a145f59f2545e49ce03681eba69c4d
Source noteuspto-grants-2009_08