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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2104728Generated: October 30, 2026

3-Aminophenylboronic acid → 4-(3-{[3-Cyano-8-(Trifluoromethyl)Quinolin-4-yl]Amino}Phenyl)-8-(Trifluoromethyl)Quinoline-3-Carbonitrile

https://huagongshe.com/reaction/2104728

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Aminophenylboronic acidHCID 92269—
Reactant4-Chloro-8-(trifluoromethyl)-3-quinolinecarbonitrileHCID 66913634—
Product4-(3-{[3-Cyano-8-(Trifluoromethyl)Quinolin-4-yl]Amino}Phenyl)-8-(Trifluoromethyl)Quinoline-3-CarbonitrileHCID 86598773—

Reaction Steps

The title compound was prepared from 4-chloro-8-(trifluoromethyl)quinoline-3-carbonitrile and 3-aminophenylboronic acid according to the procedure of Example 1 as a side product. MS (ES) m/z 531.8.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576215B2
Source datasetuspto-grants-2009_08
ORD IDord-0f90929d490c4fab8c747eebaf052e1b
Source noteuspto-grants-2009_08