Lithium Hydroxide → HCID 66914179, compound
Reaction equation
[C:1]([C:9]1[CH:10]=[N:11][C:12]2[C:17]([C:18]=1[C:19]1[CH:20]=[C:21]([NH:25][C:26]([NH:28][C:29]3[CH:30]=[C:31]([CH:36]=[CH:37][CH:38]=3)[C:32]([O:34]C)=[O:33])=[O:27])[CH:22]=[CH:23][CH:24]=1)=[CH:16][CH:15]=[CH:14][C:13]=2[C:39]([F:42])([F:41])[F:40])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Li+].[OH-]>>[C:1]([C:9]1[CH:10]=[N:11][C:12]2[C:17]([C:18]=1[C:19]1[CH:20]=[C:21]([NH:25][C:26]([NH:28][C:29]3[CH:30]=[C:31]([CH:36]=[CH:37][CH:38]=3)[C:32]([OH:34])=[O:33])=[O:27])[CH:22]=[CH:23][CH:24]=1)=[CH:16][CH:15]=[CH:14][C:13]=2[C:39]([F:42])([F:40])[F:41])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1Participants
3
Procedure
The title compound was prepared from methyl 3-{[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amino) carbonyl]amino}benzoate and LiOH according to the procedure of Example 1. MS (ES) m/z 553.9.
Sources & evidence
- ORD record
- ord-c40f6289d5a14613badf674c3d99aca3
- Source dataset
- uspto-grants-2009_08
- Patent number
- US07576215B2
Reaction notes
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