Lithium Hydroxide → HCID 66913910, compound

HRID 2104743Notes

Reaction equation

[C:1]([C:9]1[CH:10]=[N:11][C:12]2[C:17]([C:18]=1[C:19]1[CH:20]=[C:21]([CH:47]=[CH:48][CH:49]=1)[O:22][CH2:23][C:24]1[CH:29]=[CH:28][C:27]([CH:30]([CH2:35][C:36]3[CH:41]=[CH:40][C:39]([CH2:42][C:43]([O:45]C)=[O:44])=[CH:38][CH:37]=3)[C:31]([O:33]C)=[O:32])=[CH:26][CH:25]=1)=[CH:16][CH:15]=[CH:14][C:13]=2[C:50]([F:53])([F:52])[F:51])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Li+].[OH-]>>[C:1]([C:9]1[CH:10]=[N:11][C:12]2[C:17]([C:18]=1[C:19]1[CH:20]=[C:21]([CH:47]=[CH:48][CH:49]=1)[O:22][CH2:23][C:24]1[CH:29]=[CH:28][C:27]([CH:30]([CH2:35][C:36]3[CH:37]=[CH:38][C:39]([CH2:42][C:43]([OH:45])=[O:44])=[CH:40][CH:41]=3)[C:31]([OH:33])=[O:32])=[CH:26][CH:25]=1)=[CH:16][CH:15]=[CH:14][C:13]=2[C:50]([F:53])([F:51])[F:52])(=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

Reactant 2

HCID 3939Lithium Hydroxide

HCID 66913791HCID 66913791, compound

Product 1

HCID 66913910HCID 66913910, compound

Procedure

The title compound was prepared from methyl 2-[4-({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]phenoxy}methyl)phenyl]-3-[4-(2-methoxy-2-oxoethyl)phenyl]propanoate by LiOH hydrolysis. MS (ES) m/z 688.0.

Sources & evidence

ORD record: ord-9464d0d638d74648af79ce902dad5f38
Source dataset: uspto-grants-2009_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07576215B2

Reaction notes

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