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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2104780Generated: October 26, 2026

2-Thiophenecarboxaldehyde → {3-[3-Benzyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenyl}(2-Thienylmethyl)Amine

https://huagongshe.com/reaction/2104780

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-ThiophenecarboxaldehydeHCID 7364—
Reactant3-(3-Benzyl-8-trifluoromethyl-quinolin-4-yl)-phenylamineHCID 11234297—
Product{3-[3-Benzyl-8-(Trifluoromethyl)Quinolin-4-yl]Phenyl}(2-Thienylmethyl)AmineHCID 66914494—

Reaction Steps

The title compound was prepared from {3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amine and thiophene-2-carbaldehyde according to the procedure of Example 66. MS (ES) m/z 475.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576215B2
Source datasetuspto-grants-2009_08
ORD IDord-5c7c9a9456154dea9a3c873e077a1b5c
Source noteuspto-grants-2009_08