HuagongsheHuagongshe Chemistry Print Report · For research reference only
Loxoprofen Impurity 18 → HCID 66913725, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Loxoprofen Impurity 18 | HCID 11242311 | — |
| Reactant | 3-(8-Chloro-3-methylquinolin-4-yl)phenol | HCID 53411971 | — |
| Product | HCID 66913725 | HCID 66913725 | — |
Reaction Steps
This compound was prepared according to the procedure of example 41, substituting 3-(8-chloro-3-methyl-quinolin-4-yl)-phenol and 2-(4-bromomethyl-phenyl)-propionic acid methyl ester. Purification by supercritical fluid chromatography (MeOH/CO2). Electronic circular dichroism CD λmax=−4 mdeg @ 225 nm (EtOH). MS (ESI) m/z 432.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07576215B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-b6ee1b39228a4a888d9f6677deb6e759 |
| Source note | uspto-grants-2009_08 |