1-(2-Chlorophenyl)ethanol → 3-Benzyl-4-{3-[1-(2-Chlorophenyl)Ethoxy]Phenyl}-8-(Trifluoromethyl)Quinoline

HRID 2104883Notes

Reaction equation

HRID 2104883 reaction equation
[CH2:1]([C:8]1[CH:9]=[N:10][C:11]2[C:16]([C:17]=1[C:18]1[CH:19]=[C:20]([OH:24])[CH:21]=[CH:22][CH:23]=1)=[CH:15][CH:14]=[CH:13][C:12]=2[C:25]([F:28])([F:27])[F:26])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Cl:29][C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][C:31]=1[CH:36](O)[CH3:37]>>[CH2:1]([C:8]1[CH:9]=[N:10][C:11]2[C:16]([C:17]=1[C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([O:24][CH:36]([C:31]3[CH:32]=[CH:33][CH:34]=[CH:35][C:30]=3[Cl:29])[CH3:37])[CH:19]=1)=[CH:15][CH:14]=[CH:13][C:12]=2[C:25]([F:28])([F:26])[F:27])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 260821-(2-Chlorophenyl)ethanolHCID 536307553-[3-Benzyl-8-(trifluoromethyl)quinolin-4-yl]phenol

Product 1

HCID 669140423-Benzyl-4-{3-[1-(2-Chlorophenyl)Ethoxy]Phenyl}-8-(Trifluoromethyl)Quinoline

Procedure

This compound was prepared according to the procedure of example 69, substituting 3-(3-benzyl-8-trifluoromethyl-quinolin-4-yl)-phenol and 1-(2-chloro-phenyl)-ethanol. MS (ESI) m/z 519.

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-8c2799d8a29145da93ae018301aaa823
Source dataset
uspto-grants-2009_08
Patent number
US07576215B2

Reaction notes

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