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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2104883Generated: October 30, 2026

1-(2-Chlorophenyl)ethanol → 3-Benzyl-4-{3-[1-(2-Chlorophenyl)Ethoxy]Phenyl}-8-(Trifluoromethyl)Quinoline

https://huagongshe.com/reaction/2104883

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Chlorophenyl)ethanolHCID 26082—
Reactant3-[3-Benzyl-8-(trifluoromethyl)quinolin-4-yl]phenolHCID 53630755—
Product3-Benzyl-4-{3-[1-(2-Chlorophenyl)Ethoxy]Phenyl}-8-(Trifluoromethyl)QuinolineHCID 66914042—

Reaction Steps

This compound was prepared according to the procedure of example 69, substituting 3-(3-benzyl-8-trifluoromethyl-quinolin-4-yl)-phenol and 1-(2-chloro-phenyl)-ethanol. MS (ESI) m/z 519.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576215B2
Source datasetuspto-grants-2009_08
ORD IDord-8c2799d8a29145da93ae018301aaa823
Source noteuspto-grants-2009_08