2-Bromopyridine → HCID 68814979, compound

HRID 2104944Notes

Reaction equation

[CH2:1]([O:3][C:4]1[CH:5]=[C:6]([N:14]([CH2:23][C:24]2S[CH:26]=[CH:27][N:28]=2)[C:15]2[CH:22]=[CH:21][C:18]([C:19]#[N:20])=[CH:17][CH:16]=2)[CH:7]=[CH:8][C:9]=1[O:10][CH:11]([CH3:13])[CH3:12])[CH3:2].Br[C:30]1[CH:35]=CC=CN=1>>[CH2:1]([O:3][C:4]1[CH:5]=[C:6]([N:14]([CH2:23][C:24]2[CH:35]=[CH:30][CH:26]=[CH:27][N:28]=2)[C:15]2[CH:22]=[CH:21][C:18]([C:19]#[N:20])=[CH:17][CH:16]=2)[CH:7]=[CH:8][C:9]=1[O:10][CH:11]([CH3:13])[CH3:12])[CH3:2]

Participants

Reactant 2

HCID 79732-Bromopyridine

HCID 68815181HCID 68815181, compound

Product 1

HCID 68814979HCID 68814979, compound

Procedure

According to the procedure for Intermediate 2.1, 2-bromopyridine (100 mg, 0.633 mmol) afforded 177 mg of Intermediate 4.1.

Sources & evidence

ORD record: ord-f3e7401816134ba6842c891b1eb077c2
Source dataset: uspto-grants-2009_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07576098B2

Reaction notes

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