HCID 178418866, compound → HCID 178420160, compound

Participants

Reaction Steps

3-phenyl-1,2,4-triazole-5-thiol (1.80 g, 10.2 mmol) and Raney Ni (rinsed with EtOH 3×, 3 g) in 30 mL EtOH was refluxed for 1.5 h. The mixture was filtered and concentrated. The crude yellow oil was redissolved in EtOAc and filtered through 1″ SiO2, then concentrated to afford 1.32 g of Intermediate 17.1 as a white crystalline solid.

Provenance & Evidence