HRID2105

反应详情

EQUATION

反应方程式

HRID 2105 的结构方程式

AUXILIARIES

试剂、催化剂与溶剂

1

PROCEDURE

实验过程

To a solution of 3-(4-chlorobenzoyl)propionic acid (20 g) in absolute ethanol (200 ml) was added 5 g of hydrazine monohydrate. A thick solid was formed which dissolved after heating. The resulting solution was refluxed for 3 h, cooled and the solid formed filtered and dried to yield 16 g (80%) of 6-(4-chlorophenyl)-4,5-dihydropyridazinone.

WORKUP

后处理

  1. customA thick solid was formed which
  2. dissolutiondissolved
  3. temperatureafter heating
  4. temperatureThe resulting solution was refluxed for 3 h
  5. temperaturecooled
  6. customthe solid formed
  7. filtrationfiltered
  8. customdried