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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2105014Generated: October 30, 2026

4-Aminobenzonitrile → HCID 178436565, compound

https://huagongshe.com/reaction/2105014

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-AminobenzonitrileHCID 13396—
Reactant3-{[tert-Butyl(dimethyl)silyl]oxy}-5-ethyl-2-fluorobenzaldehydeHCID 59838072—
ReactantHCID 178466719HCID 178466719—
ProductHCID 178436565HCID 178436565—

Reaction Steps

According to the procedure for Intermediate 1.1, Intermediate 188.3 (3.72 g, 13.17 mmol) and 4-aminobenzonitrile (1.56 g, 13.17 mmol) afforded 5.10 g of Intermediate 188.4 as an orange oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576098B2
Source datasetuspto-grants-2009_08
ORD IDord-d9d500eb11584bd18996fa30d720609e
Source noteuspto-grants-2009_08