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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2105038Generated: October 31, 2026

4-Aminobenzonitrile → 4-(5-Ethyl-2-fluorostyryl)benzonitrile

https://huagongshe.com/reaction/2105038

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-AminobenzonitrileHCID 13396—
Reactant5-Ethyl-2-fluorobenzaldehydeHCID 57803803—
ReactantHCID 178466719HCID 178466719—
Product4-(5-Ethyl-2-fluorostyryl)benzonitrileHCID 68817259—

Reaction Steps

According to procedure for the preparation of Intermediate 1.1, 5-ethyl-2-fluorobenzaldehyde (900 mg, 5.88 mmol) and 4-aminobenzonitrile (694 mg, 5.88 mmol) afforded 950 mg of Intermediate 262.1

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576098B2
Source datasetuspto-grants-2009_08
ORD IDord-67bc6287cdcf4d958bc14483b1ea3fae
Source noteuspto-grants-2009_08