HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-1-methyl-1H-imidazole → 4-((4-bromo-1-methyl-1H-imidazol-2-yl)(5-ethyl-2-fluorophenyl)methylamino)benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-1-methyl-1H-imidazole | HCID 1277653 | — |
| Reactant | 4-((4-bromo-1-methyl-1H-imidazol-2-yl)(5-ethoxy-2-fluoro-3-isopropoxyphenyl)methylamino)benzamidine | HCID 68812975 | — |
| Reactant | 4-(5-Ethyl-2-fluorostyryl)benzonitrile | HCID 68817259 | — |
| Product | 4-((4-bromo-1-methyl-1H-imidazol-2-yl)(5-ethyl-2-fluorophenyl)methylamino)benzonitrile | HCID 68813381 | — |
Reaction Steps
According to procedure for the preparation of Intermediate 259.1, Intermediate 262.1 and 4-bromo-1-methyl-1H-imidazole afforded Intermediate 262.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07576098B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-87a9c15e6a9e472eb060956317fb4eec |
| Source note | uspto-grants-2009_08 |