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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2105039Generated: October 29, 2026

4-Bromo-1-methyl-1H-imidazole → 4-((4-bromo-1-methyl-1H-imidazol-2-yl)(5-ethyl-2-fluorophenyl)methylamino)benzonitrile

https://huagongshe.com/reaction/2105039

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-1-methyl-1H-imidazoleHCID 1277653—
Reactant4-((4-bromo-1-methyl-1H-imidazol-2-yl)(5-ethoxy-2-fluoro-3-isopropoxyphenyl)methylamino)benzamidineHCID 68812975—
Reactant4-(5-Ethyl-2-fluorostyryl)benzonitrileHCID 68817259—
Product4-((4-bromo-1-methyl-1H-imidazol-2-yl)(5-ethyl-2-fluorophenyl)methylamino)benzonitrileHCID 68813381—

Reaction Steps

According to procedure for the preparation of Intermediate 259.1, Intermediate 262.1 and 4-bromo-1-methyl-1H-imidazole afforded Intermediate 262.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07576098B2
Source datasetuspto-grants-2009_08
ORD IDord-87a9c15e6a9e472eb060956317fb4eec
Source noteuspto-grants-2009_08