HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2-Fluorophenyl)methanethiol → 2-[[(2-Fluorophenyl)methyl]thio]-4-[[(1R)-2-hydroxy-1-methylethyl]amino]-7(8H)-pteridinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2-Fluorophenyl)methanethiol | HCID 522175 | — |
| Reactant | 2-[[(2,3-Difluorophenyl)methyl]sulfonyl]-4-[[(1R)-2-hydroxy-1-methylethyl]amino]-7(8H)-pteridinone | HCID 68817193 | — |
| Product | 2-[[(2-Fluorophenyl)methyl]thio]-4-[[(1R)-2-hydroxy-1-methylethyl]amino]-7(8H)-pteridinone | HCID 68816885 | 50.7% |
Reaction Steps
The titled compound (0.089 g) was prepared by the method of Example 13, step (c) using the product from Example 13, step (a) (0.20 g) and 2-fluorobenzylmercaptan (0.083 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07579342B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-296f41c11c91408e847c0ad1bbb3ae64 |
| Source note | uspto-grants-2009_08 |