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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2105162Generated: November 1, 2026

Thenyl mercaptan → 4-[[-2-Hydroxy-1-(hydroxymethyl)ethyl]amino]-2-[(2-thienylmethyl)thio]-7(8h)-pteridinone

https://huagongshe.com/reaction/2105162

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThenyl mercaptanHCID 80408—
Reactant2-[[(2,3-Difluorophenyl)methyl]sulfonyl]-4-[[-2-hydroxy-1-hydroxymethylethyl]amino]-7(8H)-pteridinoneHCID 22505937—
Product4-[[-2-Hydroxy-1-(hydroxymethyl)ethyl]amino]-2-[(2-thienylmethyl)thio]-7(8h)-pteridinoneHCID 2250597553.5%

Reaction Steps

The titled compound (0.075 g) was prepared by the method of Example 13, step (c) using the product from example 23, step (a) (0.21 g) and 2-thienylmethylmercaptan (0.05 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07579342B2
Source datasetuspto-grants-2009_08
ORD IDord-99da3c7b59a1408ab84172c2b655c82b
Source noteuspto-grants-2009_08