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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2105167Generated: November 1, 2026

2-[[(2,3-Difluorophenyl)methyl]thio]-4,5,6-pyrimidinetriamine → 4-Amino-2-[[(2,3-difluorophenyl)methyl]thio]-6-(trifluoromethyl)-7(8H)-pteridinone

https://huagongshe.com/reaction/2105167

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-[[(2,3-Difluorophenyl)methyl]thio]-4,5,6-pyrimidinetriamineHCID 22288503—
ReactantTrifluoropyruvateHCID 22506014—
Product4-Amino-2-[[(2,3-difluorophenyl)methyl]thio]-6-(trifluoromethyl)-7(8H)-pteridinoneHCID 22506019—

Reaction Steps

The sub-titled compound was prepared from the product of Example 2, step (c) (5 g) and trifluoropyruvate (10 ml) using the method of Example 2, step (d).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07579342B2
Source datasetuspto-grants-2009_08
ORD IDord-94de552c9bc74a318c8cd84c5ac8d62f
Source noteuspto-grants-2009_08