4-Bromo-2-[[(2,3-difluorophenyl)methyl]thio]-6(trifluoromethyl)-7(8H)-pteridinone → 2-[[(2,3-Difluorophenyl)methyl]thio]-4-[[(1R)-2-hydroxy-1-methylethyl]amino]-6-(trifluoromethyl)-7(8H)-pteridinone

Participants

Role	Name	HCID	Charge
Reactant	4-Bromo-2-[[(2,3-difluorophenyl)methyl]thio]-6(trifluoromethyl)-7(8H)-pteridinone	HCID 22505958	—
Solvent	(R)-(-)-2-Amino-1-propanol	HCID 80308	—
Product	2-[[(2,3-Difluorophenyl)methyl]thio]-4-[[(1R)-2-hydroxy-1-methylethyl]amino]-6-(trifluoromethyl)-7(8H)-pteridinone	HCID 68815606	—

The titled compound was prepared from the product of example 37, step (b) (150 mg) and D-alaninol (100 μl) using the method of Example 2, step (f).