HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → HCID 87585486, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 1H-Pyrazol-3-amine, 5-methyl- | HCID 93146 | — |
| Reactant | 2,6-dichloropyrimidine-4-carboxylic acid | HCID 240530 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 87585486 | HCID 87585486 | 77% |
Reaction Steps
A mixture of 2,4-dichloropyrimidin-6-yl carboxylic acid (Method 45) (528 mg, 2.73 mmol), 3-amino-5-methylpyrazole (279 mg, 2.87 mmol) and sodium carbonate (578 mg, 5.46 mmol) was heated in water (10 ml) at 50° C. for 18 hours. The mixture was allowed to cool and the product was collected by filtration, washed with water and dried to give the title compound (430 mg, 77%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07579349B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-3417b3c794e5417eb566f8875be6aa36 |
| Source note | uspto-grants-2009_08 |