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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2105428Generated: October 26, 2026

(2S)-2-methylpyrrolidine → 7-[3-((S)-2-Methyl-pyrrolidin-1-yl)-propoxy]-3,4-dihydro-2H-2,4a,5-triaza-fluoren-1-one

https://huagongshe.com/reaction/2105428

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2S)-2-methylpyrrolidineHCID 6999702—
Reactant7-(3-chloro-propoxy)-3,4-dihydro-2H-2,4a,5-triaza-fluoren-1-oneHCID 68462729—
Product7-[3-((S)-2-Methyl-pyrrolidin-1-yl)-propoxy]-3,4-dihydro-2H-2,4a,5-triaza-fluoren-1-oneHCID 1667903019%

Reaction Steps

The title compound was synthesized in analogy to example 2, from 7-(3-chloro-propoxy)-3,4-dihydro-2H-2,4a,5-triaza-fluoren-1-one and (S)-2-methylpyrrolidine (commercially available), to give the desired product as a colorless solid (19%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07579351B2
Source datasetuspto-grants-2009_08
ORD IDord-7845984041ff4887bc6e9d0b456bf44d
Source noteuspto-grants-2009_08