HuagongsheHuagongshe Chemistry Print Report · For research reference only
O-Methylhydroxylamine hydrochloride → HCID 67506072, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | O-Methylhydroxylamine hydrochloride | HCID 521874 | — |
| Reactant | O-(propan-2-yl)hydroxylamine hydrochloride | HCID 12696235 | — |
| Reactant | N-(4-chloroquinolin-3-yl)-2-methylpropanamide | HCID 67505834 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 67506072 | HCID 67506072 | 56.3% |
Reaction Steps
The method of Part B of Example 25 was followed using N-(4-chloroquinolin-3-yl)-2-methylpropanamide (3.6 g, 14.5 mmol), O-isopropylhydroxylamine hydrochloride (1.8 g, 16 mmol) in lieu of O-methylhydroxylamine hydrochloride, and ethanol (60 mL). 1-Isopropoxy-2-isopropyl-1H-imidazo[4,5-c]quinoline (2.2 g) was obtained as a dark oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07579359B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-cd7e47c1c49741068169c0bd0a5ab835 |
| Source note | uspto-grants-2009_08 |