反应详情

The method of Part B of Example 25 was followed using N-(4-chloroquinolin-3-yl)-2-methylpropanamide (3.6 g, 14.5 mmol), O-isopropylhydroxylamine hydrochloride (1.8 g, 16 mmol) in lieu of O-methylhydroxylamine hydrochloride, and ethanol (60 mL). 1-Isopropoxy-2-isopropyl-1H-imidazo[4,5-c]quinoline (2.2 g) was obtained as a dark oil.