Glycerol → HCID 15975762, compound

Participants

Reaction Steps

Gelatin (20 kg) and concentrated glycerin (6 kg) were admixed in the presence of purified water (20 kg) at 70° C. to give homogeneous solution. (2R)-7-oxo-2-propyloctanoic acid (0.9 kg) was injected into soft capsule filling machine (rotary-type soft capsule filling machine (TYPE-H1 manufactured by KAMATA CO., LTD.)) to give wet soft capsules each containing (2S)-7-oxo-2-propyloctanoic acid. The obtained wet soft capsules were dried by tumble-dry and rack-dry sequentially, thereby obtaining above captioned soft capsules (2200 capsules) each containing 300 mg of (2S)-7-oxo-2-propyloctanoic acid.

Provenance & Evidence