Bis(2-Methoxyethyl)amine → N,N-bis-(2-methoxy-ethyl)-2-piperazin-1-yl-acetamide

HRID 2105858Notes

Reaction equation

C(O[C:6]([N:8]1[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]1)=O)(C)(C)C.ClC[C:16](Cl)=[O:17].[CH3:19][O:20][CH2:21][CH2:22][NH:23][CH2:24][CH2:25][O:26][CH3:27]>>[CH3:19][O:20][CH2:21][CH2:22][N:23]([CH2:24][CH2:25][O:26][CH3:27])[C:16](=[O:17])[CH2:6][N:8]1[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]1

Participants

Reactant 3

HCID 2383Bis(2-Methoxyethyl)amine

HCID 6577Chloroacetyl chloride

HCID 143452tert-Butyl piperazine-1-carboxylate

Product 1

HCID 57809287N,N-bis-(2-methoxy-ethyl)-2-piperazin-1-yl-acetamide

Procedure

The title compound was prepared from 1-tert-butyloxycarbonyl-piperazine, chloroacetylchloride and N,N-bis-(2-methoxy-ethyl)amine in an analogous manner as described in example 21.

Sources & evidence

ORD record: ord-05c2ee8a497a4619a6d4a171fc46a386
Source dataset: uspto-grants-2009_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07579368B2

Reaction notes

Loading…