HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → 4-(2,3-Dichlorophenyl)piperidin-4-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 57438798 | HCID 57438798 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-(2,3-Dichlorophenyl)piperidin-4-ol | HCID 62788168 | — |
Reaction Steps
According to Preparation 2: Tert-butyl 4-(2,3-dichlorophenyl)-4-hydroxypiperidine-1-carboxylate (3.0 g, 8.7 mmol), methylen chloride (50 ml), trifluoroacetic acid (10 ml). Yield: 0.88 g. MS m/z (rel. intensity, 70 eV) 246 (M+, 8), 245 (14), 212 (34), 210 (bp), 192 (67).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07579474B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-c6ed9083b342441c8587a824ea462a2d |
| Source note | uspto-grants-2009_08 |