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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2106463Generated: October 30, 2026

1,2-Dichloroethane → HCID 11784862, compound

https://huagongshe.com/reaction/2106463

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantDimethylamine, hydrochlorideHCID 10473—
ReactantHCID 11328417HCID 11328417—
Catalyst4-(Dimethylamino)pyridineHCID 14284—
ProductHCID 11784862HCID 1178486237.2%

Reaction Steps

5-{1-[4-(3,3-Dimethyl-2-oxo-butoxy)-3-methyl-phenyl]-1-ethyl-propyl}-3-methyl-benzofuran-2-carboxylic acid (520 mg, 1.154 mmol), DMAP (422 mg, 3.46 mmol), EDC (332 mg, 1.73 mmol), and dimethyl amine hydrochloride (141 mg, 1.73 mmol) are reacted analogous to Example 1, step I to give the title product (205 mg, 37%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07579488B2
Source datasetuspto-grants-2009_08
ORD IDord-fc0dc5ae65ca491aa04a8edcc5a7bd6b
Source noteuspto-grants-2009_08