Triethylamine → HCID 57810573, compound

Participants

Reaction Conditions

Reaction Steps

A solution of 1-{4-[1-ethyl-1-(5-hydroxy-benzofuran-2-yl)-propyl]-2-methyl-phenoxy}-3,3-dimethyl-butan-2-one (236 mg, 0.579 mmol) in CH2Cl2 (10 mL) was treated with methanesulfonic chloride (99 mg, 0.868 mmol) and Et3N (0.40 mL). The mixture was stirred at 0° C. for 30 min, and the reaction is quenched with MeOH (1.0 mL). The mixture is purified with EtOAc/Hexanes (25%) to obtain the title compound (260 mg, 92%). MS (ES) m/e: 504.2 (M+18).

Provenance & Evidence