HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 11293500, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 57810536 | HCID 57810536 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 11293500 | HCID 11293500 | 96% |
Reaction Steps
6-{1-[4-(3,3-Dimethyl-2-oxo-butoxy)-3-methyl-phenyl]-1-ethyl-propyl}-benzofuran-2-carboxylic acid ethyl ester (980 mg, 2.11 mmol) and NaOH (2 N, 10.0 mL) and MeOH (5.0 mL) and THF (5.0 mL) are reacted analogous to Example 2 to give the title compound (880 mg, 96%). MS (ES) m/e: 435.3 (M−1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07579488B2 |
| Source dataset | uspto-grants-2009_08 |
| ORD ID | ord-6f4127eea532453bbf4ddf61fd425a3d |
| Source note | uspto-grants-2009_08 |