Potassium Carbonate → HCID 11178032, compound

Participants

Reaction Steps

5-[1-Ethyl-1-(4-hydroxy-3-methyl-phenyl)-propyl]-7-methyl-benzofuran-2-carboxylic acid (1000 mg, 2.7 mmol), 2-chloro cyclohexanone (429 mg, 3.3 mmol) and potassium carbonate (759 mg, 5.5 mmol) was made in an analogous manner to Example 30 part D followed by base hydrolysis with 2N NaOH analogous to Example 30 part E to yield (60 mg, 30%) MS (ES) m/e: 433.3 (M−1)

Provenance & Evidence