Hydrochloric Acid → HCID 15016294, compound

HRID 2106613Notes

Reaction equation

HRID 2106613 reaction equation
C([O:3][C:4]([CH:6]([O:8][C:9]1[N:13]=[CH:12][N:11]([C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([F:20])[CH:15]=2)[N:10]=1)[CH3:7])=[O:5])C.[OH-].[K+].Cl>C(O)C>[C:4]([CH:6]([O:8][C:9]1[N:13]=[CH:12][N:11]([C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([F:20])[CH:15]=2)[N:10]=1)[CH3:7])([OH:5])=[O:3]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 14797Potassium HydroxideHCID 15016293HCID 15016293, compound

Product 1

HCID 15016294HCID 15016294, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Four g of the product of Example 57 was combined with 1.6 g of potassium hydroxide in 100 ml of ethanol, and the mixture was heated briefly to reflux. It was then cooled poured over ice-water, and made acid with hydrochloric acid. The product was collected by filtration and dried to obtain 3.4 g of the desired compound, m.p. 177°-179°.

Workup

  1. temperaturethe mixture was heated briefly
  2. temperatureto reflux
  3. temperatureIt was then cooled
  4. filtrationThe product was collected by filtration
  5. customdried

Sources & evidence

ORD record
ord-d0adc86478f54b9ca5cc4bc1e58553e6
Source dataset
uspto-grants-1990_06
Patent number
US04931083

Reaction notes

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