Methylamine → HCID 23048807, compound

HRID 2106651Notes

Reaction equation

HRID 2106651 reaction equation
O=[C:2]([C:8]1[CH:13]=[CH:12][C:11]([CH2:14][CH2:15][CH2:16][CH2:17][N:18]2[CH2:23][CH2:22][N:21]([C:24]3[CH:29]=[CH:28][C:27]([CH3:30])=[CH:26][CH:25]=3)[CH2:20][CH2:19]2)=[CH:10][CH:9]=1)[CH2:3][CH2:4][C:5]([OH:7])=O.[CH3:31][NH2:32]>>[CH3:31][N:32]1[CH:2]([C:8]2[CH:13]=[CH:12][C:11]([CH2:14][CH2:15][CH2:16][CH2:17][N:18]3[CH2:19][CH2:20][N:21]([C:24]4[CH:25]=[CH:26][C:27]([CH3:30])=[CH:28][CH:29]=4)[CH2:22][CH2:23]3)=[CH:10][CH:9]=2)[CH2:3][CH2:4][C:5]1=[O:7]

Participants

3

Reactant 2

HCID 6329MethylamineHCID 14423685HCID 14423685, compound

Product 1

HCID 23048807HCID 23048807, compound

Procedure

4-Oxo-4-[4-(4-(4-(4-methylphenyl)piperazin-1-yl)butyl)phenyl]butyric acid and methylamine are reacted together to give N-methyl-5-[4-(4-(4-(4-methylphenyl)piperazin-1-yl)butyl)phenyl]pyrrolidin-2-one.

Sources & evidence

ORD record
ord-9b1cc4dce47e49b8883f5a99e1965587
Source dataset
uspto-grants-1990_06
Patent number
US04931443

Reaction notes

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