1-[2-(Piperidin-4-yl)ethyl]piperidine → HCID 14369627, compound

HRID 2106676Notes

Reaction equation

HRID 2106676 reaction equation
Cl[C:2]([N:4]1[C:10]2[CH:11]=[CH:12][CH:13]=[CH:14][C:9]=2[C:8](=[O:15])[NH:7][C:6]2[CH:16]=[CH:17][CH:18]=[N:19][C:5]1=2)=[O:3].[N:20]1([CH2:26][CH2:27][CH:28]2[CH2:33][CH2:32][NH:31][CH2:30][CH2:29]2)[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21]1>>[N:20]1([CH2:26][CH2:27][CH:28]2[CH2:33][CH2:32][N:31]([C:2]([N:4]3[C:10]4[CH:11]=[CH:12][CH:13]=[CH:14][C:9]=4[C:8](=[O:15])[NH:7][C:6]4[CH:16]=[CH:17][CH:18]=[N:19][C:5]3=4)=[O:3])[CH2:30][CH2:29]2)[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25]1

Participants

3

Reactant 2

HCID 2962921-[2-(Piperidin-4-yl)ethyl]piperidineHCID 1104396211-chlorocarbonyl-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one

Product 1

HCID 14369627HCID 14369627, compoundYield 47%

Procedure

Prepared analogously to Example 4 from 11-(chlorocarbonyl)-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one and 4-[2-(1-piperidinyl)ethyl]piperidine in a yield of 47% of theory. Colourless crystals, m.p. 178°-180° C.

Sources & evidence

ORD record
ord-1c7d160b54e04627a039d3c40c649f46
Source dataset
uspto-grants-1990_06
Patent number
US04931436

Reaction notes

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