1-Methyl-4,4'-bipiperidine → HCID 14369629, compound

HRID 2106677Notes

Reaction equation

HRID 2106677 reaction equation
[Cl:1][C:2]([N:4]1[C:10]2[CH:11]=[CH:12][CH:13]=[CH:14][C:9]=2[C:8](=[O:15])[NH:7][C:6]2[CH:16]=[CH:17][CH:18]=[N:19][C:5]1=2)=[O:3].[CH3:20][N:21]1[CH2:26][CH2:25][CH:24]([CH:27]2[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]2)[CH2:23][CH2:22]1>>[ClH:1].[CH3:20][N:21]1[CH2:26][CH2:25][CH:24]([CH:27]2[CH2:32][CH2:31][N:30]([C:2]([N:4]3[C:10]4[CH:11]=[CH:12][CH:13]=[CH:14][C:9]=4[C:8](=[O:15])[NH:7][C:6]4[CH:16]=[CH:17][CH:18]=[N:19][C:5]3=4)=[O:3])[CH2:29][CH2:28]2)[CH2:23][CH2:22]1

Participants

3

Reactant 2

HCID 71830411-Methyl-4,4'-bipiperidineHCID 1104396211-chlorocarbonyl-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one

Product 1

HCID 14369629HCID 14369629, compoundYield 21%

Procedure

Prepared analogously to Example 4 from 11-(chlorocarbonyl)-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one and 4-(1-methyl-4-piperidinyl)piperidine in a yield of 21% of theory. Colourless crystals, m.p. 254°-255° C.

Sources & evidence

ORD record
ord-25d0446e73eb4fb19a8c1f49125a5f46
Source dataset
uspto-grants-1990_06
Patent number
US04931436

Reaction notes

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