反应详情

Prepared analogously to Example 4 from 11-(chlorocarbonyl)-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepin-5-one and 3-[2-(hexahydro-1H-1-azepinyl)ethyl]piperidine in a yield of 58% of theory. Colourless crystals, m.p. 152°-154° C. (acetonitrile), Rf 0.64 (Macherey-Nagel, Polygram® SIL G/UV254, pre-coated plastic sheets for TLC; eluant: dichloromethane/cyclohexane/methanol/conc. ammonia 68/15/15/2, v/v/v/v)