HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 15057352, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 11-(chlorocarbonyl)-5,11-dihydro-8-methyl-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one | HCID 14209977 | — |
| Reactant | 2-[2-(1-Piperidinyl)ethyl]morpholine | HCID 15057327 | — |
| Product | HCID 15057352 | HCID 15057352 | 79% |
Reaction Steps
Prepared analogously to Example 4 from 11-(chlorocarbonyl)-5,11-dihydro-8-methyl-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one and 2-[2-(1-piperidinyl)ethyl]morpholine in a yield of 79% of theory. Rf 0.43 (conditions as in Example 58). The colourless hydrochloride melted at 272°-273° C. with decomposition.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04931436 |
| Source dataset | uspto-grants-1990_06 |
| ORD ID | ord-2e64fc64377c4369913e4620c844e26c |
| Source note | uspto-grants-1990_06 |