HCID 14350368, compound → 4-(Chloromethyl)-2-(4-chlorophenyl)-1,3-thiazole

Participants

Reaction Steps

11.95 g (40 mmol) of the 4-chlorothiobenzimidic acid-3-chloroacetonyl ester hydrochloride obtained in (b) were introduced into 40 ml concentrated sulphuric acid at room temperature, with stirring, left to stand at room temperature for 30 minutes and then poured onto ice. The crystallate was drawn off, washed free of acid with water, and dried.

Provenance & Evidence