1,2-Dichloroethane → 6-Methoxy-4-oxo-8-piperazin-1-yl-4H-chromene-2-carboxylic acid (4-morpholin-4-yl-phenyl)-amide

HRID 210715Notes

Reaction equation

HRID 210715 reaction equation
[Cl:36][C:37]([O:38][CH:39]([Cl:40])[CH3:41])=[O:42].[Cl:45][CH2:46][CH2:47][Cl:48].[I-:44].[Na+:43].[O:1]1[CH2:2][CH2:3][N:4]([c:7]2[cH:8][cH:9][c:10]([NH:13][C:14](=[O:15])[c:16]3[o:17][c:18]4[c:19]([N:29]5[CH2:30][CH2:31][N:32]([CH3:35])[CH2:33][CH2:34]5)[cH:20][c:21]([O:27][CH3:28])[cH:22][c:23]4[c:24](=[O:26])[cH:25]3)[cH:11][cH:12]2)[CH2:5][CH2:6]1>>[O:1]1[CH2:2][CH2:3][N:4]([c:7]2[cH:8][cH:9][c:10]([NH:13][C:14](=[O:15])[c:16]3[o:17][c:18]4[c:19]([N:29]5[CH2:30][CH2:31][NH:32][CH2:33][CH2:34]5)[cH:20][c:21]([O:27][CH3:28])[cH:22][c:23]4[c:24](=[O:26])[cH:25]3)[cH:11][cH:12]2)[CH2:5][CH2:6]1

Participants

6

Reactant 5

HCID 111,2-DichloroethaneHCID 923Sodium ionHCID 30165Iodide IonHCID 5213051-Chloroethyl chloroformateHCID 235333236-Methoxy-8-(4-methyl-piperazin-1-yl)-4-oxo-4H-chromene-2-carboxylic acid (4-morpholin-4-yl-phenyl)-amide

Product 1

HCID 235333256-Methoxy-4-oxo-8-piperazin-1-yl-4H-chromene-2-carboxylic acid (4-morpholin-4-yl-phenyl)-amide

Sources & evidence

ORD record
ord-59a73c9dcdef4d01a2f51ff747c41b5a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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