Ammonia → HCID 86744020, compound

HRID 2107156Notes

Reaction equation

HRID 2107156 reaction equation
[NH2:1][C:2]1[S:3][CH:4]=[C:5]([C:7](=O)[C:8]([O:10][CH2:11][CH3:12])=[O:9])[N:6]=1.[S:14]1[CH2:20][C:18](=[O:19])[N:17]([CH2:21][C:22]([OH:24])=[O:23])[C:15]1=[S:16].[Cl-].[NH4+].N>C(O)C>[OH2:9].[NH2:1][C:2]1[S:3][CH:4]=[C:5]([C:7](=[C:20]2[S:14][C:15](=[S:16])[N:17]([CH2:21][C:22]([OH:24])=[O:23])[C:18]2=[O:19])[C:8]([O:10][CH2:11][CH3:12])=[O:9])[N:6]=1

Participants

6

Reactant 4

HCID 222AmmoniaHCID 25517Ammonium ChlorideHCID 797933-Thiazolidineacetic acid, 4-oxo-2-thioxo-HCID 4356513Ethyl 2-(2-Amino-4-thiazolyl)-2-oxoacetate

Product 1

HCID 86744020HCID 86744020, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The desired compound was prepared by reacting at room temperature, for 15 minutes, 20 g of ethyl 2-aminothiazol-4-ylglyoxylate, 22.9 g of rhodanine-3-acetic acid, 11 g of ammonium chloride, 15 ml of 28% v/v aqueous ammonia and 200 ml of ethanol, following a procedure similar to that described in Example 1. The resulting orange product had the following physical properties.

Sources & evidence

ORD record
ord-440b614deee142e7b71f71a85ccfa7b1
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

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